Xanax

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Alprazolam was first released by Upjohn (now a part of Pfizer) in 1981. The first approved use was of panic disorder, and within two years of its original marketing, Xanax became a blockbuster drug in the US. As of 2010, alprazolam is the most prescribed and the most misused benzodiazepine in the US. The potential for misuse among those taking it for medical reasons is controversial, with some expert reviews stating that the risk is low and similar to that of other benzodiazepine drugs. Others state that there is a substantial risk of misuse and dependence in both patients and non-medical users and that the high affinity binding, high potency, short elimination half-life, and rapid onset of action may increase the misuse potential of alprazolam. Compared to the large number of prescriptions, relatively few individuals increase their dose on their own initiative or engage in drug-seeking behavior. Alprazolam is classified as a Schedule IV controlled substance by the U. S. Drug Enforcement Administration (DEA).

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